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Bemegride (INN) and its salts

CAS 64-65-3
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A CNS stimulant pharmaceutical agent that is banned from cosmetic use due to high acute toxicity and dangerous systemic effects.

Bemegride is a respiratory stimulant drug (analeptic) historically used to counteract barbiturate overdose. It is classified as an INN (International Nonproprietary Name) substance and is absolutely prohibited in cosmetic products under EU Regulation (EC) No 1223/2009 (Annex II). The hazard profile shows acute oral, dermal, and inhalation toxicity (H300, H311, H331) with a Danger signal word. It has no legitimate use in topical cosmetic formulations.

Known concerns

  • Acute oral toxicity (H300)
  • Acute dermal toxicity (H311)
  • Acute inhalation toxicity (H331)
  • EU Annex II - banned substance
  • Danger signal word

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.