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Neurocosmetic peptide

BICYCLIC S-KINOSHITA'S CONE OLIGOPEPTIDE-2 TRIFLUOROACETATE

55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic peptide modeled on cone snail venom toxins, supplied as a trifluoroacetate salt. Pitched for muscle-relaxing, anti-wrinkle effects, with very limited public safety review.

Skin benefits

  • Conotoxin-inspired oligopeptide may target specific receptors
  • Potential anti-aging or neurocosmetic claims via peptide signalling
  • Used at very low concentrations in serums

Known concerns

  • Cone snail venom-derived peptides have potent biological activity
  • Trifluoroacetate counterion is a persistent environmental contaminant
  • No public CIR or SCCS safety review for this specific peptide
  • Limited independent human safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.