Skin Conditioning
2-METHYL-4-HYDROXYPYRROLIDINE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A small amino-alcohol cyclic compound used as a skin conditioning agent. Secondary amine class — nitrosamine formation is a formulation-stewardship concern.
2-Methyl-4-hydroxypyrrolidine (CAS 94134-94-8) is a small five-membered nitrogen heterocycle with a methyl and a hydroxyl substituent. As a secondary amine, it belongs to a class where co-formulation with nitrosating agents (sodium nitrite, some preservatives) can produce carcinogenic nitrosamines — a concern thoroughly studied in DEA/TEA/MEA compounds. There is no CIR or SCCS review specific to this ingredient. Public safety and efficacy data in cosmetics is limited; default-cautious scoring is appropriate. Typical cosmetic use is likely at low concentration.
Skin benefits
- Small heterocyclic amine — potential skin conditioning
- Possible role as pH buffer or humectant precursor
Known concerns
- Secondary amine — potential nitrosamine formation with nitrosating agents (nitrites)
- No dedicated CIR or SCCS review
- Limited public safety data
- Small-amine class generally requires tighter formulation controls
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.