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dihydrocodeine

CAS 125-28-0
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A narcotic opioid analgesic and controlled substance classified CMR, prohibited in cosmetic products under EU Cosmetics Regulation Annex II.

Dihydrocodeine is a semi-synthetic opioid analgesic derived from codeine, used in some jurisdictions as a prescription analgesic and anti-tussive. It is classified as a controlled substance (Schedule II/III depending on jurisdiction) and CMR under EU CLP. It is prohibited under EU Cosmetics Regulation Annex II and has no established safe or authorised use in cosmetic products.

Known concerns

  • CMR substance
  • Banned under EU Cosmetics Regulation Annex II
  • Opioid controlled substance
  • Dependence and respiratory depression risk

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.