Not permitted in cosmetics
fluocinolone acetonide
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A prescription corticosteroid drug — not a cosmetic ingredient. A recurring adulterant in illegal skin-lightening creams; never permitted in legitimate cosmetics.
Fluocinolone acetonide (CAS 67-73-2) is a medium-potency fluorinated topical corticosteroid prescribed for inflammatory dermatoses. It is not a permitted cosmetic ingredient in the EU (not on CosIng as cosmetic use) or the US (Rx drug). Fluocinolone acetonide is one of the most frequently detected illegal corticosteroid adulterants in brightening creams; repeated exposure causes steroid-induced rosacea, skin atrophy, telangiectasia, and rebound dermatitis. Documented HPA-axis suppression on large-surface-area or occluded application.
Skin benefits
- Prescription anti-inflammatory activity (not a cosmetic benefit)
Known concerns
- Medium-potency topical corticosteroid — prescription-only drug
- Skin atrophy, telangiectasia, striae with repeated use
- HPA-axis suppression with extensive/occluded use
- Not permitted in cosmetic products in EU/US
- Common adulterant in unregulated brightening creams
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related not permitted in cosmeticss
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.