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Midodrine hydrochloride [USAN:JAN]

CAS 3092-17-9
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Midodrine hydrochloride [USAN:JAN] is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Midodrine hydrochloride (CAS 3092-17-9) is classified under GHS/CLP with hazard statements H301 (acute toxicity — swallowing), H302 (harmful if swallowed), H312 (harmful in contact with skin), H317 (skin sensitization), H319 (eye irritation), H332 (harmful if inhaled), H335 (respiratory irritation), and H361 (suspected reproductive toxicity). This is a pharmaceutical substance with no cosmetic application, and its presence in any EU-market cosmetic product is prohibited under Regulation (EC) No 1223/2009 as it constitutes an unauthorized drug substance.

Known concerns

  • H301/H302/H312/H332: Acute toxicity on multiple exposure routes
  • H317: Skin sensitization potential
  • H361: Suspected reproductive toxicant
  • Prescription drug — prohibited in EU cosmetics
  • Severe cardiovascular effects if absorbed through skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Midodrine hydrochloride [USAN]
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.