Prohibited in cosmetics
Morphine sulfate
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A controlled opioid pharmaceutical — absolutely never a cosmetic ingredient. Any listing is an error or diversion; this should never appear in consumer skincare.
Morphine sulfate (CAS 64-31-3) is a Schedule II opioid analgesic in the US, a Class A/B controlled drug under the UK Misuse of Drugs Act, and a UN Single Convention narcotic. It is strictly regulated for medical/hospital use only. It is not a permitted cosmetic ingredient anywhere; its INCI-style listing indicates database misidentification or an illegal/diverted product. Topical absorption is limited but non-zero, and systemic opioid effects (respiratory depression, sedation, dependence) are well documented. There is no cosmetic scenario in which this belongs on a consumer product.
Skin benefits
- No cosmetic benefit — controlled substance
Known concerns
- Opioid controlled substance (Schedule II US / UN narcotic)
- Not permitted in any cosmetic product worldwide
- Systemic toxicity including respiratory depression
- Presence in cosmetics indicates gross misidentification or diversion
- EU Annex II-equivalent regulatory prohibition
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related prohibited in cosmeticss
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.