Other
Nitrofurantoin (INN)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Nitrofurantoin (inn) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Nitrofurantoin is a broad-spectrum urinary antiseptic of the nitrofuran class, used exclusively as a human antibiotic drug. It is prohibited in cosmetic products because it is a pharmacologically active substance not permitted for cosmetic use and is listed on EU Annex II (banned substances). Nitrofurantoin is notably associated with severe adverse skin reactions including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, as well as chronic photosensitivity and peripheral neuropathy. There is no cosmetic application that could justify inclusion of this drug.
Known concerns
- Prohibited pharmacologically active substance — EU Annex II
- Severe cutaneous adverse reactions (erythema multiforme, SJS, TEN)
- Photosensitivity
- Antibiotic resistance ecological concern
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.