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prenalterol

CAS 57526-81-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Prenalterol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Prenalterol (INN) is a synthetic phenethylamine derivative functioning as a selective beta-1 adrenoceptor agonist. It was investigated as a cardiotonic agent for heart failure but its development was limited by tachyphylaxis and safety concerns. As a pharmacological agent with no history of cosmetic use and significant cardiovascular activity, it would be prohibited under EU Regulation 1223/2009 Article 14, which prohibits substances with pharmacological or immunological action intended to modify physiological functions.

Known concerns

  • Pharmaceutical drug with beta-1 agonist activity — prohibited cosmetic ingredient
  • Cardiovascular effects (positive inotropy, tachycardia risk)
  • No safety assessment for cosmetic topical use
  • Likely classified as a substance with pharmacological action under EU cosmetics law

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.