2,2,2-Trichloroethane-1,1-diol
Other
Avoid
CAS Number: 302-17-0
About 2,2,2-Trichloroethane-1,1-diol
Chloral hydrate — a withdrawn sedative drug that is an IARC Group 2A probable carcinogen. Not a cosmetic ingredient.
Detailed Analysis
2,2,2-Trichloroethane-1,1-diol (chloral hydrate, CAS 302-17-0) is a sedative-hypnotic drug with a long but problematic history of medical use as an insomnia and pediatric sedation agent; it has been withdrawn from many markets on safety grounds (narrow therapeutic index, cardiac and respiratory depression, overdose lethality). IARC classifies chloral hydrate as Group 2A (probably carcinogenic to humans) on the basis of animal liver tumour evidence. It is not an authorised cosmetic ingredient and has no cosmetic function. Any listing in a cosmetic database reflects regulatory/CMR watch-listing rather than formulation use.
Skin Benefits
- ✓ None for cosmetic use
Known Concerns
- ⚠ IARC Group 2A probable human carcinogen
- ⚠ Withdrawn sedative drug
- ⚠ Not a cosmetic ingredient
- ⚠ Systemic CNS toxicity
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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