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6-Nitro-o-toluidine

CAS 570-24-1
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-substituted aromatic amine with significant mutagenicity and carcinogenicity concerns, subject to severe EU restrictions as a hazardous intermediate.

6-Nitro-o-toluidine (2-methyl-6-nitroaniline) is a nitroaromatic compound with significant safety concerns. Its PubChem safety score is 10, reflecting substantial toxicity. Nitroaromatic compounds are well-known for their mutagenic and carcinogenic properties. The structural alert from the nitro group combined with the aromatic amine creates multiple concerns for genetic damage and cancer. It is not permitted in cosmetic products under EU Regulation 1223/2009 due to severe safety concerns.

Known concerns

  • Severe mutagenicity concerns
  • Suspected carcinogen (nitroaromatic)
  • EU banned/restricted substance
  • Significant genotoxic potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.