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tiomesterone

CAS 2205-73-4
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tiomesterone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Tiomesterone is an anabolic-androgenic steroid (chemically a 19-nortestosterone derivative with a thio group at C-17). It has no cosmetic application and no safety data relevant to topical cosmetic exposure. Like all anabolic steroids, it is regulated as a pharmaceutical substance in most jurisdictions. The EU Cosmetics Regulation Annex II prohibits substances with pharmacological activity, and anabolic steroids fall squarely in this category. No SCCS assessment exists because there is no plausible legitimate cosmetic use. The score of 5 reflects near-zero safety margin and regulatory prohibition in the EU and most global markets.

Known concerns

  • EU Annex II banned — prohibited in all cosmetic products
  • Anabolic steroid — pharmacological activity with systemic effects
  • No cosmetic function — no safety data for topical application
  • Regulated pharmaceutical in most jurisdictions
  • Endocrine disruptor potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.