Other
1-Chloro-2,3-epoxypropane (Epichlorohydrin)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
1-chloro-2,3-epoxypropane (epichlorohydrin) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Epichlorohydrin (1-chloro-2,3-epoxypropane) is a reactive epoxide with one of the most severe hazard profiles in the cosmetics regulatory framework. It is listed in EU Annex II (prohibited substances) and carries multiple CLP hazard classifications including H350 (may cause cancer), H340 (may cause genetic defects), H361 (suspected of damaging fertility or the unborn child), H311 (toxic in contact with skin), and H314 (causes severe skin burns). The compound is used almost exclusively as a chemical intermediate in industrial processes and is never intentionally added to cosmetic formulations.
Known concerns
- Prohibited in EU cosmetics (Annex II)
- Carcinogen (H350 - IARC Group 2A)
- Mutagen (H340)
- Reproductive toxicant (H361)
- Acute toxicity multiple routes
- Severe skin burns (H314)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.