1,1,3,3,5-Pentamethyl-4,6-dinitroindane (Moskene)

22

Avoid

CAS Number: 116-66-5

About 1,1,3,3,5-Pentamethyl-4,6-dinitroindane (Moskene)

A cosmetic ingredient. Exercise caution due to limited available safety data.

Detailed Analysis

Moskene is a synthetic nitro-musks fragrance ingredient. Nitro-musks have raised environmental concerns due to their persistence, bioaccumulation potential, and transformation products in the environment. While less commonly regulated than some other nitroaromatics, the EU's precautionary approach to nitro-musks in general has led to restrictions. The CosIng database lists restrictions for this substance at concentrations >=0.1% in mixtures.

Known Concerns

  • ⚠ Environmental persistence (PBT-like behaviour)
  • ⚠ Bioaccumulation potential
  • ⚠ Nitroaromatic structural concerns

Safety Score

22

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.