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1,1,3,3,5-Pentamethyl-4,6-dinitroindane (Moskene)

CAS 116-66-5
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cosmetic ingredient. Exercise caution due to limited available safety data.

Moskene is a synthetic nitro-musks fragrance ingredient. Nitro-musks have raised environmental concerns due to their persistence, bioaccumulation potential, and transformation products in the environment. While less commonly regulated than some other nitroaromatics, the EU's precautionary approach to nitro-musks in general has led to restrictions. The CosIng database lists restrictions for this substance at concentrations >=0.1% in mixtures.

Known concerns

  • Environmental persistence (PBT-like behaviour)
  • Bioaccumulation potential
  • Nitroaromatic structural concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.