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1,2,3,4,4A,5,6,7-OCTAHYDRO-2,5,5-TRIMETHYL-2-NAPHTHOL

CAS 41199-19-3
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A tricyclic sesquiterpene alcohol (santanol derivative) with skin irritation and environmental toxicity warnings, used at controlled concentrations in fine fragrances.

1,2,3,4,4A,5,6,7-Octahydro-2,5,5-trimethyl-2-naphthol (also known as alpha-santalol derivative or similar tricyclic santalane-type structure) carries H315 (skin irritation) and H412 (aquatic chronic toxicity) classifications. The tricyclic sesquiterpene structure is related to sandalwood-type fragrances but with skin irritating potential. It is not listed in EU Annex III restrictions but must be used within IFRA guidelines. The sandalwood/santalol family has extensive use in perfumery with established safety at controlled concentrations.

Known concerns

  • Skin irritation (H315)
  • Aquatic chronic toxicity (H412)
  • Fragrance allergen consideration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.