Antioxidant
1,2,4-TRIHYDROXYBENZENE
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A reactive phenolic compound (hydroxyhydroquinone) used in skin lightening research. Classed as a skin sensitizer with toxicity flags, and falls under EU hydroquinone-class restrictions.
Function
Skin benefits
- Inhibits tyrosinase in lab studies
- Antioxidant activity in vitro
Known concerns
- Known skin sensitizer
- Possible genotoxicity
- Acute oral toxicity
- EU hydroquinone-class restrictions
- Risk of paradoxical hyperpigmentation
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.