1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione

22

Avoid

CAS Number: 59653-74-6

About 1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione

A triglycidyl isocyanurate compound with severe toxicity including mutagenicity, skin and respiratory sensitization, explicitly restricted in EU.

Detailed Analysis

1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione (CAS 59653-74-6) is an epoxy-substituted triazine trione, structurally similar to TGIC. GHS hazard statements include H301 (toxic if swallowed), H302 (harmful if swallowed), H315 (causes skin irritation), H317 (may cause skin sensitization), H318 (causes serious eye damage), H319 (causes serious eye irritation), H331 (toxic if inhaled), H334 (may cause allergy or asthma if inhaled), H340 (may cause genetic defects), H361 (suspected of damaging fertility), H373 (may cause damage to organs), H412 (harmful to aquatic life). The substance shares TGIC's epoxy and triazine structure, giving it similar mutagenic and sensitization concerns. EU REACH restricts this substance. Cosmetic use is highly questionable and likely prohibited.

Known Concerns

  • ⚠ Mutagenic (H340)
  • ⚠ Skin sensitization (H317)
  • ⚠ Respiratory sensitization (H334)
  • ⚠ Reproductive toxicity (H361)
  • ⚠ Acute toxicity (H301, H331)
  • ⚠ Aquatic toxicity (H412)

Safety Score

22

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

🏛

EU CosIng Database

European Commission cosmetic ingredient registry

Check your products for 1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione

Scan any cosmetic product to see if it contains this ingredient and get a full safety breakdown.

Download LuxSense

This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.