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1,3-benzenediol

CAS 108-46-3
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

1,3-benzenediol is a cosmetic ingredient. Exercise caution due to limited available safety data.

Resorcinol (CAS 108-46-3) functions as a antiseptic, antioxidant, and coupling agent in hair dye and acne treatment formulations. EU Regulation 1223/2009 Annex III restricts its use in cosmetic products. The compound carries extensive hazard statements including H302 (harmful if swallowed), H315 (causes skin irritation), H317 (may cause allergic skin reaction), H319 (causes serious eye irritation), H370 (causes damage to organs), H371 (may cause damage to organs), H372 (causes damage to organs through prolonged or repeated exposure), and H400/H410 (aquatic toxicity). Studies have suggested potential thyroid hormone disruption from resorcinol exposure, leading to restrictive concentration limits.

Skin benefits

  • Antiseptic properties for acne treatment
  • Used as coupling agent in oxidative hair dyeing
  • Provides color development in hair dye formulations

Known concerns

  • Maximum 0.5% in rinse-off EU products
  • Thyroid hormone disruption potential
  • Skin and respiratory sensitizer (H317/H334)
  • Organ toxicity from repeated exposure (H372)
  • Aquatic toxicity (H400/H410)
  • Extensive hazard profile requires careful handling

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.