1,3-BIS-(2,4-DIAMINOPHENOXY)PROPANE
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
1,3-bis-(2,4-diaminophenoxy)propane is a cosmetic ingredient used in product formulations. Note: subject to regulatory restrictions in some markets. Exercise caution due to limited available safety data.
This compound is listed in EU Annex III (restricted substances) under entry III/202, indicating it may be used in cosmetic products only under specified conditions — typically in oxidative hair dye formulations at a maximum concentration and with required label warnings. Aromatic diamines are known skin sensitisers and the restriction reflects concerns about allergic contact dermatitis risk in hair dye applications.
Known concerns
- Skin sensitiser — known to cause allergic contact dermatitis
- EU Annex III/202 restricted hair dye intermediate
- Aromatic diamine structure associated with sensitisation
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.