Skip to content

Synthetic pigment intermediate

1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline

CAS 8003-22-3
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An industrial reaction product of phthalic anhydride with quinolines used as a yellow colorant. Quinoline chemistry and limited public safety data place it in the cautious range for cosmetic transparency.

Skin benefits

  • Yellow industrial pigment intermediate (Solvent Yellow 33-type) used as colorant
  • High tinctorial strength at low loadings
  • Stable in many cosmetic vehicles
  • Useful for shade adjustment in color cosmetics

Known concerns

  • Quinoline-based pigments are tied to genotoxicity concerns in some assessments
  • Reaction-product profile means impurities and isomers vary by lot
  • Not on EU permitted colorant list for general cosmetic use under this CAS
  • Limited skin-contact safety data published

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline in your products.

Scan any cosmetic product with LuxSense to see if it contains 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.