1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic ingredient. Exercise caution due to limited available safety data.
The reaction product of 1,3-isobenzofurandione (phthalic anhydride) with methylquinoline and quinoline is a dye preparation. EU Cosmetics Regulation restricts this substance from use in products applied on mucous membranes, indicating a safety concern with membrane contact. The restriction reflects potential toxicity with prolonged mucous membrane exposure, though it may be used in other cosmetic applications with appropriate labelling.
Known concerns
- Not permitted in products applied on mucous membranes
- Quinoline derivatives may have mutagenic potential
- Restriction reflects mucous membrane toxicity concern
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.