1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1, CI 64500) is an anthraquinone disperse dye used in hair dye formulations. It carries the Danger signal word with hazard classifications including H315, H317, H318 (skin and eye damage), H350 (carcinogenicity), H351 (suspected carcinogenicity), and H373 (organ toxicity). The EU Annex III listing restricts its use as a hair dye substance. The four amino groups on the anthraquinone ring create a highly conjugated system associated with photosensitivity reactions and potential genotoxicity through oxidative stress mechanisms.
Known concerns
- EU Annex III restricted hair dye with labeling requirements
- Carcinogenicity (H350) - Category 1B
- Suspected carcinogen (H351)
- Skin irritant and sensitizer (H315, H317)
- Serious eye damage (H318)
- Organ toxicity through repeated exposure (H373)
- Photosensitivity concerns from anthraquinone structure
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.