Skip to content

Other

1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.

CAS 68953-84-4
34

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This ingredient is a commercial mixture of phenylenediamine and tolylenediamine derivatives — the same chemical class as well-known hair dye sensitisers such as PPD and PTD. These aromatic amines are known for causing severe allergic contact dermatitis in sensitised individuals and are subject to specific EU restrictions when used in oxidative hair dye systems. The mixture is not formally listed in EU Annexes as a specific entry, but each component aromatic amine falls under the general hair dye restrictions in Annex III.

Skin benefits

  • Functions as a hair dye intermediate in oxidative colourant systems
  • Contributes to permanent hair colouring through oxidative coupling reactions

Known concerns

  • Known contact allergens — risk of severe allergic contact dermatitis
  • Structural alerts for nitrosation and azo reduction
  • Potential aromatic amine impurity profile raises concern
  • Risk of cross-reactivity with other phenylenediamine derivatives
  • EU Annex III restrictions apply to constituent aromatic amines

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

34
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate
Other
 34
Betamethasone
Other
 34
NONOXYNOL-14
Other
 35
1,3-Benzenediamine, 4-methyl-, hydrochloride (1:1)
Other
 35
1,5-Di-(beta-hydroxyethylamino)-2-nitro-4-chlorobenzene (see note 17)
Other
 35
2,2'-Methylenebis(6-bromo-4-chlorophenol)
Other
 35
2,4-DIAMINO-5-METHYLPHENETOLE HCL
Other
 35
2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL
Other

Check your shelf

Find 1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs. in your products.

Scan any cosmetic product with LuxSense to see if it contains 1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs. and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.