prohibited
1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A mixed phenyl and tolyl phenylenediamine derivative. EU regulators classify it as a CMR substance and have added it to Annex II, banning it from cosmetic products.
Skin benefits
- No accepted cosmetic benefit at this point
- Historic use in oxidative hair dyes
- Industrial antioxidant for rubber, not cosmetics
- Not relevant for new formulations
Known concerns
- Classified CMR (carcinogen, mutagen or reprotoxicant)
- Added to EU Cosmetics Regulation Annex II of prohibited substances
- EU Omnibus Act VII requires withdrawal from cosmetics by September 2025
- Phenylenediamines linked to strong allergic reactions
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related prohibiteds
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.