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1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea

CAS 101-20-2
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A urea-based antibacterial agent structurally related to triclocarban, toxic to aquatic life and under EU review for endocrine-disrupting potential.

This chlorinated phenylurea compound is structurally related to triclocarban, which is banned in EU cosmetics under Annex II. It carries H400/H410 (aquatic toxicity) warnings and is subject to EU REACH restrictions on organohalogen compounds. The chlorophenyl-urea structure is associated with concerns about environmental persistence and potential endocrine activity.

Skin benefits

  • Antimicrobial function for preservation

Known concerns

  • Aquatic toxic (H400/H410)
  • EU REACH organohalogen restrictions
  • Related to banned triclocarban
  • Environmental persistence concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.