1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8,-hexamethyl-2-naphthyl)ethan-1-one (AHTN)
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-Hexamethyl-2-Naphthyl)Ethan-1-One (AHTN, Trade name: Tonalide) is a polycyclic aromatic nitromusk fragrance. It is listed in EU Annex III with specific concentration limits: 0.1% in leave-on products (except 1% in hydroalcoholic products, 2.5% in fine fragrances, and 0.5% in fragrance creams) and 0.2% in rinse-off products. AHTN is persistent in the environment, has been detected in aquatic organisms and human adipose tissue, and is classified as H411 (toxic to aquatic life with long-lasting effects). The hexamethyl tetralone structure is associated with environmental bioaccumulation concerns.
Skin benefits
- Provides long-lasting musky, floral fragrance
- Excellent fixative properties
Known concerns
- EU Annex III restricted with concentration limits by product type
- Persistent in environment with bioaccumulation potential
- Detected in human tissues
- Aquatic toxicity (H411)
- Environmental concerns have led to declining use despite regulatory permissibility
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.