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1-Anilino-4-hydroxyanthraquinone

CAS 19286-75-0
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

1-Anilino-4-hydroxyanthraquinone is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

1-Anilino-4-Hydroxyanthraquinone is an anthraquinone disperse dye with restriction to rinse-off products only under EU cosmetics regulation. The anthraquinone scaffold is associated with photosensitivity reactions, and the anilino substituent raises concerns for genotoxicity. The restriction to rinse-off products indicates the EU has determined the risk profile is acceptable only for products that are not left on the skin. The dye structure contains aromatic amine and quinone functionalities, both of which have been associated with mutagenicity in test systems.

Skin benefits

  • Provides coloration to rinse-off cosmetic products

Known concerns

  • EU restriction to rinse-off products only
  • Potential genotoxicity from anilino-anthraquinone structure
  • Photosensitivity concerns
  • Possible mutagenic activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.