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1-Methoxy-2,5-diaminobenzene (2,5-Diaminoanisole) and its salts

CAS 5307-02-8
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2,5-Diaminoanisole is an oxidative hair dye precursor carrying multiple hazard statements: H302/H312 (acute oral/dermal toxicity), H317 (skin sensitisation), H332 (inhalation toxicity), and H334 (respiratory sensitisation). Hair dye intermediates are restricted under EU Annex III with specific conditions. The methoxy substitution on the benzene ring influences its dyeing chemistry and toxicological profile.

Skin benefits

  • Enables oxidative hair coloration with specific tone

Known concerns

  • Acute oral and dermal toxicity (H302/H312)
  • Skin sensitiser (H317)
  • Respiratory sensitiser (H334)
  • EU Annex III hair dye restrictions apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.