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1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)

CAS 104-46-1/ 4180-23-8
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

trans-Anethole (1-methoxy-4-(1E)-1-propen-1-ylbenzene) is listed in EU Annex III of the Cosmetics Regulation under reference number 67, with a maximum concentration of 0.001% in leave-on products when used as a fragrance allergen. The H317 classification confirms skin sensitization potential, and H412 indicates chronic aquatic toxicity. While permitted at low concentrations, its allergenicity and environmental profile require careful formulation control.

Skin benefits

  • Provides aromatic properties to cosmetic formulations

Known concerns

  • Skin sensitizer (H317 - may cause an allergic skin reaction)
  • Hazardous to aquatic life with long-lasting effects (H412)
  • EU Annex III fragrance allergen with concentration limit 0.001% in leave-on products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.