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Reactive monomer (CMR)

1-Vinyl-2-pyrrolidone

CAS 88-12-0
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A reactive monomer used to produce PVP polymers, classified as a carcinogen in the EU. It is not permitted as an intentional cosmetic ingredient and only appears as a tightly limited residual impurity.

Skin benefits

  • Industrial monomer to make safe polyvinylpyrrolidone polymers
  • Not intentionally used as a finished cosmetic ingredient

Known concerns

  • Classified as Carcinogen Category 1B in EU CLP
  • Limited evidence of carcinogenicity (IARC Group 2B historically; ECHA harmonized as carc.)
  • Prohibited as a CMR substance in EU cosmetics under Annex II framework
  • Residual monomer in polymers must be tightly controlled
  • Irritant to skin, eyes and respiratory tract

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.