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1-Vinyl-2-pyrrolidone

CAS 88-12-0
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

1-Vinyl-2-pyrrolidone is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

1-Vinyl-2-Pyrrolidone (N-Vinylpyrrolidone, NVP) is listed in EU Annex III of the Cosmetics Regulation with restriction to a maximum of 0.1% in the final ready-to-use preparation. The H351 classification indicates suspected carcinogenicity, and the vinyl group confers reactivity and potential for polymerization. The compound has been associated with concerns regarding reproductive toxicity and developmental effects at high doses. The restriction limit reflects the EU's precautionary approach to suspected carcinogens in cosmetic products.

Known concerns

  • Suspected carcinogen (H351)
  • EU Annex III restricted to maximum 0.1% in ready-to-use preparations
  • Suspected mutagenic potential
  • Vinyl monomer with reactivity concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.