1H-Pyrazole-4,5- diamine, 1-hexyl-, sulfate (2:1)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A hexyl-substituted pyrazole diamine used as a hair dye intermediate, carrying severe acute toxicity, organ toxicity, and sensitization hazards. Subject to Danger signal word classification and significant EU regulatory restrictions.
1H-Pyrazole-4,5-Diamine, 1-hexyl-, sulfate (2:1) is a hair dye intermediate with the Danger signal word and multiple serious hazard classifications including H301+H331 (acute toxicity), H317 (sensitization), H372 (organ toxicity), and H411 (aquatic toxicity). The pyrazole diamine structure is characteristic of certain hair dye intermediates under EU regulatory scrutiny. While it may not be explicitly listed in Annex II (banned substances), the combined acute toxicity and organ toxicity profile suggests severe restrictions apply, and it is assessed as presenting significant safety concerns for cosmetic use.
Known concerns
- Acute toxicity - fatal if swallowed or inhaled (H301+H331)
- Skin sensitizer (H317)
- Causes damage to organs through prolonged or repeated exposure (H372)
- Toxic to aquatic life with long-lasting effects (H411)
- Danger signal word indicates severe hazards
- Hexyl-substituted aromatic amine - potential genotoxicity concerns
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.