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2-(2,2-DIMETHOXY)ETHOXY-P-PHENYLENEDIAMINE

CAS 2839861-10-6
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-(2,2-Dimethoxy)ethoxy-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This phenylenediamine derivative contains a dimethoxy-ethoxy side chain that increases its polarity and affects diffusion into the hair shaft during the coloring process. The acetal moiety in the side chain raises concerns regarding potential hydrolysis to release formaldehyde under acidic conditions or during storage. EU cosmetic regulation requires hair dye intermediates with no fully evaluated safety profiles to undergo stringent restriction under Annex III. Consumers should be informed about potential sensitization risks, and professional use recommendations often accompany products containing such novel aromatic amine derivatives.

Known concerns

  • Possible formaldehyde release from acetal group under acidic conditions
  • Skin sensitization potential
  • Limited long-term toxicological data
  • Hydrolysis products may be reactive

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.