2,2,6-Trimethyl-4-piperidyl benzoate (eucaine) and its salts
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A local anesthetic pharmaceutical compound not approved for cosmetic use in the EU, with structural similarity to cocaine and ester-type anesthetic risks.
Eucaine (2,2,6-trimethyl-4-piperidyl benzoate) is an ester-type local anesthetic structurally related to cocaine. Ester-type anesthetics are associated with allergic contact dermatitis and methemoglobinemia. It is not listed in EU CosIng and is not permitted in cosmetic products under Regulation 1223/2009.
Known concerns
- Not approved for cosmetic use in EU
- Ester-type anesthetic with sensitization risk
- Potential for methemoglobinemia
- Allergic contact dermatitis risk
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.