2,2,6-Trimethyl-4-piperidyl benzoate (eucaine) and its salts
Avoid
CAS Number: 500-34-5
About 2,2,6-Trimethyl-4-piperidyl benzoate (eucaine) and its salts
A local anesthetic pharmaceutical compound not approved for cosmetic use in the EU, with structural similarity to cocaine and ester-type anesthetic risks.
Detailed Analysis
Eucaine (2,2,6-trimethyl-4-piperidyl benzoate) is an ester-type local anesthetic structurally related to cocaine. Ester-type anesthetics are associated with allergic contact dermatitis and methemoglobinemia. It is not listed in EU CosIng and is not permitted in cosmetic products under Regulation 1223/2009.
Known Concerns
- ⚠ Not approved for cosmetic use in EU
- ⚠ Ester-type anesthetic with sensitization risk
- ⚠ Potential for methemoglobinemia
- ⚠ Allergic contact dermatitis risk
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.