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2-(2-METHOXYETHOXY)-P-PHENYLENEDIAMINE

CAS 344340-75-6
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-(2-Methoxyethoxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This p-phenylenediamine derivative bears a 2-methoxyethoxy (-O-CH2-CH2-O-CH3) side chain, which is a longer alkoxy chain compared to the methoxymethoxy analogue. The extended ethylene glycol monomethyl ether substituent modifies both the physicochemical properties and the toxicological profile of the parent PPD molecule. Under EU Cosmetics Regulation Annex III, oxidative hair dye intermediates including this derivative are permitted at specific concentrations with mandatory labelling. Skin sensitization remains the primary concern for this class of compounds.

Known concerns

  • Skin sensitizer - hair dye intermediate class
  • EU Annex III restricted with concentration limits
  • Mandatory sensitization labelling

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.