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2,2'-THIOBIS(4-CHLOROPHENOL)

CAS 97-24-5
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2,2'-THIOBIS(4-CHLOROPHENOL) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2,2'-Thiobis(4-chlorophenol) (Fentichlor) is a chlorinated phenolic compound with antimicrobial properties historically used as a preservative and antibacterial agent in cosmetics. The EU CLP classification as Danger with multiple hazard statements (H315 skin irritation, H317 skin sensitization, H318 serious eye damage, H335 respiratory irritation, H413 aquatic toxicity) reflects its challenging safety profile. Its use in modern cosmetics is limited due to these concerns.

Skin benefits

  • Antimicrobial/antibacterial properties
  • Historical preservative use

Known concerns

  • EU Danger classification (GHS05/GHS07)
  • H317 - skin sensitization (strong sensitizer)
  • H318 - serious eye damage potential
  • H413 - hazardous to aquatic environment
  • Not recommended for modern cosmetic formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.