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Fragrance

2,3-DIHYDRO-2,2,6-TRIMETHYLBENZALDEHYDE

CAS 116-26-7
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Safranal — the characteristic aroma compound of saffron. Natural alpha,beta-unsaturated aldehyde with Michael-acceptor structural alert.

Under CAS 116-26-7, this material corresponds to safranal (2,6,6-trimethyl-1,3-cyclohexadien-1-carboxaldehyde), the principal aroma compound of saffron. FEMA GRAS (3389) as flavor; naturally present in Crocus sativus. Chemically it is an alpha,beta-unsaturated aldehyde, which is a structural alert for Michael-acceptor reactivity and sensitization. Some in vitro genotoxicity signals exist at high concentrations. RIFM/IFRA evaluated. Not on EU Annex II.

Function

PERFUMING

Skin benefits

  • Saffron aroma character
  • Naturally sourced from saffron

Known concerns

  • Michael-acceptor sensitization alert
  • In vitro genotoxicity signals at high dose
  • Oxidation stability
  • Dermal clinical data limited

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.