2,3-Dinitrotoluene
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
2,3-dinitrotoluene is a cosmetic ingredient. Raw material is classified as a suspected carcinogen. Exercise caution due to limited available safety data.
2,3-Dinitrotoluene (CAS 602-01-7) is a nitro-substituted toluene derivative that has been used in chemical synthesis. EU Regulation 1223/2009 Annex II prohibits the use of dinitrotoluenes in cosmetic products. The compound carries extensive hazard statements including H301/H311/H331 (toxic if swallowed, in contact with skin, or if inhaled), H341 (suspected genetic defects), H350 (may cause cancer), H361 (reproductive toxicity), H370/H372 (organ toxicity), and H400/H410 (aquatic toxicity). 2,3-Dinitrotoluene is metabolically activated to reactive intermediates that form DNA adducts, explaining its mutagenic and carcinogenic potential.
Known concerns
- EU Annex II banned - nitroaromatic carcinogen
- Metabolic activation to DNA-damaging intermediates
- Confirmed mutagen (H341)
- Reproductive toxicity (H361)
- Acute toxicity by multiple routes
- Bioaccumulative potential
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.