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2,4-Diaminophenoxyethanol, its hydrochloride and its sulphate

CAS 70643-19-5 / 66422-95-5 / 70643-20-8
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An aromatic amine hair dye precursor with sensitization potential, restricted in EU hair dye formulations due to acute toxicity and allergic contact dermatitis concerns.

2,4-Diaminophenoxyethanol (CAS 70643-19-5) and its salts function as primary intermediates in oxidative hair dyeing processes. Under EU Regulation 1223/2009 Annex III, these compounds are restricted to concentrations below 0.1% as a constituent of substances or mixtures. The compounds carry hazard statements H302 (harmful if swallowed), H317 (may cause allergic skin reaction), H319 (causes serious eye irritation), and H411 (toxic to aquatic life with long lasting effects), indicating significant safety concerns that require careful formulation control.

Skin benefits

  • Essential hair dye intermediate for dark shades
  • Used in oxidative hair coloring formulations

Known concerns

  • Restricted to <0.1% in EU mixtures
  • Skin sensitizer (H317)
  • Acute oral toxicity (H302)
  • Eye irritation hazard (H319)
  • Aquatic environmental hazard (H411)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.