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2,4-DIMETHYL-3-CYCLOHEXENE CARBOXALDEHYDE

CAS 68039-49-6
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An alpha,beta-unsaturated aldehyde fragrance with citrus and herbal notes that carries inherent sensitization risk due to its reactive electrophilic double bond system.

2,4-Dimethyl-3-cyclohexene carboxaldehyde is an unsaturated cyclic aldehyde with a reactive double bond conjugated to the aldehyde group. Alpha,beta-unsaturated aldehydes are well-known contact allergens due to their ability to form covalent adducts with skin proteins. Limited specific toxicological data for this compound warrants caution.

Skin benefits

  • Provides complex citrus-green fragrance notes in cosmetic products

Known concerns

  • Alpha,beta-unsaturated aldehyde is a structural alert for sensitization
  • Reactive electrophilic center can form hapten-protein complexes in skin
  • Insufficient independent safety data for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.