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2-[(4-Methoxy-2-nitrophenyl)azo]-3-oxo-N-(o-tolyl)butyramide

CAS 6371-96-6
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This compound is a substituted azoaryl butyramide used as a colorant in rinse-off cosmetic products, with a specific EU restriction limiting its use to rinse-off formulations only. Azo dyes of this type are subject to EU Annex III restrictions under Regulation (EC) No 1223/2009; their potential to split into aromatic amines (including some carcinogenic arylamines) upon reduction in skin metabolism is a recognized concern. The rinse-off restriction is specifically mandated to limit dermal exposure.

Skin benefits

  • Provides color to rinse-off cosmetic products

Known concerns

  • Potential skin sensitizer with repeated exposure
  • Azo bond cleavage may generate aromatic amine residues
  • Restricted to rinse-off products only per EU Annex III

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.