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Fragrance CMR (banned)

2-(4-tert-butylbenzyl) propionaldehyde

CAS 80-54-6
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Better known as Lilial or Butylphenyl Methylpropional, this floral aldehyde is banned in EU cosmetics since March 2022 after being classified as CMR Category 1B reproductive toxicant under Omnibus IV.

Skin benefits

  • Historically used as a lily-of-the-valley floral aldehyde imparting a powdery muguet character
  • Was a workhorse perfumery ingredient in personal care, laundry and home fragrance

Known concerns

  • Banned in EU cosmetics since 1 March 2022 under Commission Regulation (EU) 2021/1902 (Omnibus IV)
  • Classified CMR Category 1B as toxic to reproduction based on animal fertility and foetal development studies
  • Listed in Annex II of EU Cosmetics Regulation 1223/2009, so any product containing it must be removed from market
  • Also a recognized fragrance contact allergen in addition to its CMR endpoint

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.