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Dioxane fragrance

2,5,5-TRIMETHYL-2-PHENYL-1,3-DIOXANE

CAS 5406-58-6
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2,5,5-Trimethyl-2-phenyl-1,3-dioxane is a phenyl dioxane acetal used as a fragrance ingredient in perfumery. Cosmetic-specific safety review is limited and hydrolytic stability warrants caution.

Skin benefits

  • Used as a fragrance ingredient providing floral note
  • Stable acetal structure useful in perfumery

Known concerns

  • 1,3-Dioxane scaffold raises concerns about possible release of formaldehyde or related aldehydes on hydrolysis
  • Limited dedicated cosmetic safety review for this specific isomer
  • Fragrance allergen labeling status warrants caution

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.