2,6,6-TRIMETHYLCYCLOHEXENE-1-CARBALDEHYDE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cyclic alpha,beta-unsaturated aldehyde with gem-dimethyl substitution, used as a fragrance component. The aldehyde group and double bond together create significant reactivity, with warnings for acute toxicity and multiple irritation endpoints.
2,6,6-Trimethylcyclohexene-1-Carbaldehyde is an alpha,beta-unsaturated aldehyde with gem-dimethyl substitution at C2. The combination of an aldehyde group with an adjacent double bond (alpha,beta-unsaturation) significantly increases electrophilic reactivity, raising concerns for skin protein binding and sensitization. Multiple hazard classifications (H302, H312, H315, H319, H332, H335) indicate acute toxicity and irritation potential across multiple exposure routes. It is not listed in EU Annex II or III, but the hazard profile warrants caution in formulation.
Skin benefits
- Provides citrus, herbal fragrance notes
Known concerns
- Alpha,beta-unsaturated aldehyde - high reactivity and sensitization potential
- Acute oral, dermal, and inhalation toxicity classifications
- Skin, eye, and respiratory irritation (H315, H319, H335)
- Acute dermal toxicity (H312)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.