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2,6-DIAMINO-3-((PYRIDIN-3-YL)AZO)PYRIDINE

CAS 28365-08-4
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A pyridine-based azo dye with hazard statements H302, H373, H411 requiring caution; structurally similar to hair dye intermediates restricted in EU Annex III.

This pyridyl-azo-pyridine compound carries hazard statements H302 (harmful if swallowed), H373 (may cause organ damage through prolonged exposure), and H411 (toxic to aquatic life). The azo bond in a pyridine heterocyclic system can be reduced under certain conditions to release potentially harmful aromatic amines. While not specifically restricted in EU cosmetics, the hazard profile and structural similarity to restricted hair dye intermediates warrant caution. The compound requires careful formulation control and would likely be restricted to rinse-off applications only.

Known concerns

  • H302 harmful if swallowed
  • H373 potential organ damage with prolonged exposure
  • H411 aquatic toxicity
  • Azo dye reduction concern
  • Similar to restricted hair dye intermediates

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.