2,6-DIMETHOXY-3,5-PYRIDINEDIAMINE HCL
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A pyridine heterocyclic diamine used as an oxidative hair dye intermediate, restricted in the EU under Annex III/232 due to skin sensitisation concerns.
This compound is listed in EU CosIng Annex III/232, which covers hair dye substances requiring special labelling. H301 (acute toxicity), H317 (skin sensitisation), H319 (eye irritation), and H373 (organ effects) are serious hazard classifications. The presence of two methoxy groups on the pyridine ring increases lipophilicity and dermal penetration. Hair dye use requires caution statement labelling under EU rules.
Skin benefits
- Used in oxidative hair dyeing for permanent colour
Known concerns
- Annex III/232: EU restriction for hair dye use
- H301/H317/H319/H373: acute toxicity, sensitisation, eye and organ effects
- Respiratory sensitisation risk during powder handling
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.