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2,6-Pyridinediamine, 3-(3- pyridinylazo)

CAS 28365-08-4
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A pyridyl-azo-pyridine hair dye intermediate restricted in the EU to a maximum of 0.25% in ready-for-use preparations.

This compound is a pyridine-based azo dye precursor classified under EU Cosmetics Regulation Annex III, restricted to a maximum concentration of 0.25% in hair dye formulations. While not banned, it requires caution due to potential genotoxic metabolites formed during oxidative hair dyeing processes. It is not permitted in non-oxidative hair dye applications.

Known concerns

  • EU Annex III restricted (0.25% max in oxidative hair dyes)
  • Potential genotoxic metabolite formation
  • Requires coupling agents for safe use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.