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2-Benzyl-2-dimethylamino-4'- morpholinobutyrophenone

CAS 119313-12-1
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A photoinitiator compound used in UV-cured gels and coatings with significant hazard warnings including developmental toxicity and aquatic toxicity, classified as Dangerous.

2-Benzyl-2-dimethylamino-4'-morpholinobutyrophenone (CAS 119313-12-1) is an alpha-amino ketone photoinitiator primarily used in UV/LED-curable nail gels, resins, and industrial coatings rather than conventional skincare. It carries the GHS Danger classification with H360D (developmental toxicity), H318 (serious eye damage), H361 (reproductive toxicity), H400/H410/H411 (aquatic toxicity), H360 (teratogenicity concern). The H360D developmental toxicity flag is particularly disqualifying for cosmetic use, as EU Annex II substances with developmental toxicity concern are prohibited. This substance is not listed in EU cosmetic regulation annexes and would not receive SCCS approval given the reproductive and developmental toxicity profile.

Skin benefits

  • Functions as a UV photoinitiator for nail gel curing

Known concerns

  • H360D - clear developmental toxicity concern
  • H318 - serious eye damage
  • H361 - reproductive toxicity
  • H400/H410/H411 - very toxic to aquatic organisms
  • UV photoinitiator not appropriate for skin exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.