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Hair dye (nitro)

2-[bis(2-Hydroxye­thyl)amino]-5-nitro­phenol

CAS 59820-43-8
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Known as HC Yellow 4, this is a nitro-aromatic direct hair dye restricted under EU Cosmetics Regulation Annex III with strict concentration limits and warnings about sensitization and nitrosamine formation.

Skin benefits

  • Provides yellow to orange shades in oxidative hair dye
  • Direct dye that does not require oxidation
  • Allows nuance shading in semi-permanent formulations

Known concerns

  • Nitro-aromatic hair dye with potential skin sensitization
  • EU Annex III restricted with maximum concentration limits
  • Concerns over nitrosamine impurities in formulation
  • Not suitable for eyelash or eyebrow tinting
  • Patch testing recommended due to allergy risk

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.