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2-[bis(2-Hydroxye­thyl)amino]-5-nitro­phenol

CAS 59820-43-8
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-[bis(2-hydroxye­thyl)amino]-5-nitro­phenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This nitro-phenol with bis-hydroxyethyl substitution has no listed hazard statements, suggesting an acceptable safety profile at permitted concentrations. The dual hydroxyl groups increase water solubility and reduce the likelihood of skin penetration compared to less-substituted nitro compounds. It is not restricted under EU Annex II or III and is used as a coupler in oxidative hair dyeing.

Known concerns

  • Limited long-term sensitization data
  • General nitro compound caution

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.