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2-Butanone oxime

CAS 96-29-7
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-Butanone oxime is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2-Butanone oxime (also called methyl ethyl ketoxime or MEKO) is used in cosmetics primarily as an antioxidant and fragrance fixative. ECHA classifies it with H312 skin absorption concerns and it has shown evidence of liver toxicity in chronic animal studies. It is not currently restricted in EU cosmetic regulation but is under REACH evaluation for potential reproductive effects.

Known concerns

  • Skin sensitization potential
  • Liver toxicity in chronic exposure (animal studies)
  • Suspected reproductive toxicity (REACH evaluation)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.