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2-Chloracetamide

CAS 79-07-2
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-Chloracetamide is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2-Chloracetamide is a halogenated amide that has been used as a cosmetic preservative, but is now recognized as a skin sensitization agent. It is not specifically listed in EU Annexes II or III, but it has been evaluated by the SCCS as a potential allergen and sensitizer in cosmetic products. The compound's amide structure and halogen substitution create concern for skin reactivity. Modern cosmetic formulations have largely moved away from chloroacetamide preservatives due to the availability of safer alternatives. IFRA has noted restrictions on this ingredient in fragrance and cosmetic contexts.

Skin benefits

  • Historically used as a preservative, now largely discontinued

Known concerns

  • Known skin sensitizer
  • Documented contact allergy risk
  • Not recommended for use in modern cosmetic formulations
  • Restricted in several jurisdictions due to sensitization concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.