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(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride

CAS 40722-80-3
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride carries H317 (skin sensitizer), H340 (suspected mutagen), H350 (suspected carcinogen), and H373 (specific organ toxicity) classifications. The 2-chloroethyl group is a well-known alkylating agent alert associated with mutagenicity and carcinogenicity. It is not listed in EU cosmetic regulation Annexes but its severe hazard profile absolutely contraindicates cosmetic use. The combination of sensitizing, mutagenic, and carcinogenic potential makes this compound one of the most concerning in this batch.

Known concerns

  • Suspected mutagen (H340)
  • Suspected carcinogen (H350)
  • Skin sensitizer (H317)
  • Specific organ toxicity (H373)
  • Chlorinated alkylating agent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.