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UV Filter

2-Ethylhexyl 4-methoxycinnamate / Octinoxate

CAS 5466-77-3 Updated
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Octinoxate — a widely-used UVB filter. Effective and well-tolerated topically, but flagged for estrogenic activity and reef toxicity, prompting EU re-evaluation.

Skin benefits

  • UVB filter (UV-B 280-320nm)
  • Lightweight oil-soluble texture
  • Boosts SPF

Known concerns

  • Endocrine disruption signals (estrogenic activity)
  • SCCS recently re-opened safety review
  • Banned in Hawaii / Palau for reef toxicity
  • Photo-instability

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.